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Understanding & Healing Acne (chap. 1 of 12)
Heal cycle-dependent acne naturally with NED-ZM: Hormonal balance, microbiome recalibration & scientifically proven strategies. Get your free eBook now!

Sophie
Feb 121 min read



Aferdita
Nov 13, 20251 min read


(NEWS) Wholegrain rye & CRP: 12-week RCT shows 17% less inflammation
A new 12-week RCT in 255 adults shows that wholegrain rye lowers CRP by 17% and raises butyrate/acetate, although weight loss stays similar.

Norman Reffke
5 days ago6 min read


(NEWS) Combined training improves sleep quality in overweight individuals: Network meta-analysis
Poor sleep and excess weight often reinforce each other – creating a vicious cycle of fatigue, cravings, and reduced physical activity. A new network meta-analysis of 17 randomized controlled trials with 927 adults now shows that combined endurance and strength training most reliably improves subjective sleep quality, closely followed by strength training alone. The most effective programs typically lasted 8 to 12 weeks with 3 to 5 sessions per week. Important: More isn't alw

Aferdita
Apr 156 min read


(NEWS) Sleep coaching + circuit training: RCT shows improved sleep quality in young women
A new RCT demonstrates that combining sleep coaching with high-intensity circuit training significantly improves sleep efficiency and metabolic health in young women.

Norman Reffke
Apr 95 min read


(NEWS) Nitrate-rich vegetables & endothelial function: Meta-analysis shows improvement in vascular health
Meta-analysis (13 RCTs) shows: Inorganic nitrate from beetroot & spinach improves endothelial function by 1.48% FMD – a key marker for heart health.

Norman Reffke
Apr 15 min read


(NEWS) Cardiorespiratory fitness: Meta-analysis shows 36% lower risk of depression
A new meta-analysis (Nature Mental Health, 2026) shows: high cardiorespiratory fitness is associated with 36% lower depression risk and 39% lower dementia risk.

Norman Reffke
Mar 256 min read


(NEWS) Progressive muscle relaxation: Meta-analysis shows strong effects on sleep & anxiety
A 2026 meta-analysis (31 RCTs, 2,277 participants) shows progressive muscle relaxation significantly improves sleep quality and reduces anxiety.

Norman Reffke
Mar 234 min read


(NEWS) Strength training & brain age: RCT shows how weight training can lower biological brain age
An RCT with 309 older adults shows: moderate and heavy resistance training can measurably reduce biological brain age by up to 2.3 years.

Aferdita
Mar 205 min read


(NEWS) CAG-170: Meta-analysis (n=11,115) discovers unknown health signature in the gut
A Cell Host & Microbe meta-analysis (11,115 metagenomes) identifies CAG-170 as the strongest health signature in the human gut – reevaluating the uncultured microbiome.

Norman Reffke
Mar 185 min read


(NEWS) HICT & Sleep Health: RCT shows synergy effect on sleep efficiency & wake times
8-week RCT (n=112): HICT + sleep health improves sleep efficiency by +2.75% & reduces wake after sleep onset by 16 min. – Synergy effect confirmed.

Norman Reffke
Mar 175 min read


(NEWS) Saturated fatty acids & heart health: Meta-analysis shows risk-dependent effect on mortality
Meta-analysis: Replacing saturated fat with PUFAs reduces heart attack, stroke & mortality in high-risk patients – no effect at low cardiovascular risk.

Aferdita
Mar 165 min read


(NEWS) Nature-based interventions & mental health: Umbrella review shows moderate evidence
28 meta-analyses, 344 studies – Nature-based interventions (forests, parks, gardens) moderately reduce tension, fatigue & negative affect; 89% low credibility

Sophie
Mar 146 min read


(NEWS) Metabolic Syndrome & 4 Habits: RCT shows +46% remission after 24 months
618 participants, 24 months – 4 simple habits increase MetS remission by 46% (OR=1.46, p<0.05): vegetables, walking, mindfulness, emotion regulation

Aferdita
Mar 135 min read


(NEWS) Weight loss medication & yo-yo effect: Meta-analysis shows +0.4 kg/month after stopping medication
37 studies, 9,341 participants – Meta-analysis shows +0.4 kg/month weight regain after stopping weight-loss medications. Return to baseline weight after 1.7 years.

Aferdita
Mar 134 min read


(NEWS) Wall Sit & Blood Pressure: Meta-analysis shows superiority over endurance training
Isometric exercises like wall sits lower blood pressure by 8.24/4.00 mmHg on average – more than endurance or strength training, JAMA meta-analysis shows.

Aferdita
Mar 125 min read


(NEWS) Fiber & exercise: Combined effect strengthens gut microbiome and massively reduces inflammation
24-week trial: Fiber + exercise boost microbiome diversity (+12.8%), reduce hs-CRP (-42%) & IL-6 (-35%). Butyrate as key mediator.

Norman Reffke
Mar 114 min read


(NEWS) Collagen vs. Whey: Meta-analysis shows collagen's superiority for muscle building
78 studies, 4,755 participants – Collagen outperforms whey protein: +41% strength gain, +94% fat-free mass. Meta-analysis reveals.

Aferdita
Mar 104 min read


(NEWS) 3 nights of sleep deprivation & heart risk: Study shows changes in biomarkers – What the research says
Just 3 nights sleep restriction (4.25h) alter 25 cardiovascular biomarkers – increased heart disease risk (p=0.006). Exercise cannot fully compensate effects.

Norman Reffke
Mar 94 min read


(NEWS) Ultra-processed foods: 47% higher risk of heart attack – Large US study reveals alarming links
Ultra-processed foods, Heart attack, Stroke, Cardiovascular disease, NHANES study, Lancet Series, Nutritional prevention, Chronic inflammation, Metabolic syndrome, Health policy, Food industry, Evidence-based nutrition, UPF

Norman Reffke
Mar 83 min read


Understanding muscle soreness: Why it occurs, what biochemical processes are behind it, and how you can treat it effectively.
Discover why DOMS occurs, the biochemical processes involved, and how omega-3, curcumin & co. accelerate muscle recovery scientifically.

Aferdita
Mar 79 min read


(NEWS) Flexible school start times & teenagers' sleep: Swiss study shows +44 minutes of sleep per night
New study (n=2,641): Flexible school start increases sleep by 44 min/night, reduces fatigue by 14% & improves grades by 3.5% – What parents & schools need to know.

Sophie
Mar 74 min read


(NEWS) Plastics & Disease Burden: Lancet analysis shows 83 million DALYs by 2040
Lancet analysis: Plastics lifecycle causes cumulative 83M DALYs by 2040. Primary production is main driver. System change could save 43% DALYs.

Sophie
Mar 64 min read


(NEWS) Grip strength & chair stand test in women: Cohort study shows effect on mortality – What the research says
5,472 women, 8.4-year follow-up – Grip strength ≥24 kg: 33% lower mortality risk. Chair-stand <11s: 31% reduction. What the JAMA study shows.

Norman Reffke
Mar 56 min read


(NEWS) Time-Restricted Eating (TRE) & Weight Loss: Meta-analysis shows effect on fat mass & body weight – What the research says
New meta-analysis (30 RCTs, n=1341) confirms: TRE reduces fat mass (-1.50 kg) even with equal calories. All about effects & application.

Norman Reffke
Mar 45 min read


Breakthrough in urticaria therapy: First oral BTK inhibitor drug awaits EU approval
2 Phase-III trials, 925 participants – 31% symptom-free vs. 10% placebo, itch reduction from week 1, first oral BTK inhibitor therapy (p<0.001)

Norman Reffke
Mar 35 min read


(NEWS) Probiotics & Gut Microbiota: Meta-analysis shows no effects on diversity in healthy individuals – What the research says
22 RCTs, 1,068 participants – Probiotic supplementation does not significantly change gut microbiota diversity in healthy individuals (Shannon: p>0.05)

Sophie
Mar 24 min read


The daily 7-in-1 combination: How pineapple, papaya, beetroot, sour cherry, omega-3, lemon juice and barley grass can transform your health
What happens biochemically when you combine pineapple, omega-3, and beetroot? Discover the power of the 7-Combo for energy, anti-inflammation, and cell protection.

Norman Reffke
Mar 26 min read


(NEWS) Early Time-Restricted Eating & Insulin: Meta-analysis shows benefits
Time-Restricted Eating, Early Eating Window, Intermittent Fasting, Chrononutrition, Circadian Rhythm, Insulin Sensitivity, Fasting Insulin, Blood Glucose, Weight Management, Waist Circumference, Triglycerides, Metabolic Health, Fasting Window

Aferdita
Mar 13 min read


(NEWS) Antibiotic resistance & food safety: ECDC report shows progress & challenges
EU Monitoring 2023–2024: Ciprofloxacin resistance in Salmonella/Campylobacter high, but declines in 14+ countries – One Health remains essential

Norman Reffke
Feb 286 min read



Norman Reffke
Feb 271 min read



Norman Reffke
Feb 271 min read



Norman Reffke
Feb 271 min read



Norman Reffke
Feb 271 min read



Norman Reffke
Feb 271 min read



Norman Reffke
Feb 271 min read



Norman Reffke
Feb 271 min read



Norman Reffke
Feb 271 min read



Norman Reffke
Feb 271 min read


(NEWS) RSV vaccination for adults 50+: New evidence 2025/2026 shows 58-75% protection – Germany & USA compared
New meta-analyses 2025/26: RSV vaccination in adults 50+ shows 58-75% protection against hospitalization. CDC & STIKO compared – current evidence, effectiveness, safety.

Norman Reffke
Feb 277 min read


(chap. 12 of 12) Understanding & Healing Acne
Heal cycle-dependent acne naturally with NED-ZM: Hormonal balance, microbiome recalibration & scientifically proven strategies. Get your free eBook now!

Sophie
Feb 261 min read


(chap. 11 of 12) Understanding & Healing Acne
Heal cycle-dependent acne naturally with NED-ZM: Hormonal balance, microbiome recalibration & scientifically proven strategies. Get your free eBook now!

Sophie
Feb 261 min read


(chap. 10 of 12) Understanding & Healing Acne
Heal cycle-dependent acne naturally with NED-ZM: Hormonal balance, microbiome recalibration & scientifically proven strategies. Get your free eBook now!

Sophie
Feb 261 min read


(chap. 9 of 12) Understanding & Healing Acne
Heal cycle-dependent acne naturally with NED-ZM: Hormonal balance, microbiome recalibration & scientifically proven strategies. Get your free eBook now!

Sophie
Feb 261 min read


(chap. 8 of 12) Understanding & Healing Acne
Heal cycle-dependent acne naturally with NED-ZM: Hormonal balance, microbiome recalibration & scientifically proven strategies. Get your free eBook now!

Sophie
Feb 261 min read


(chap. 7 of 12) Understanding & Healing Acne
Heal cycle-dependent acne naturally with NED-ZM: Hormonal balance, microbiome recalibration & scientifically proven strategies. Get your free eBook now!

Sophie
Feb 261 min read


(chap. 6 of 12) Understanding & Healing Acne
Heal cycle-dependent acne naturally with NED-ZM: Hormonal balance, microbiome recalibration & scientifically proven strategies. Get your free eBook now!

Sophie
Feb 261 min read


(chap. 5 of 12) Understanding & Healing Acne
Heal cycle-dependent acne naturally with NED-ZM: Hormonal balance, microbiome recalibration & scientifically proven strategies. Get your free eBook now!

Sophie
Feb 261 min read


(chap. 4 of 12) Understanding & Healing Acne
Heal cycle-dependent acne naturally with NED-ZM: Hormonal balance, microbiome recalibration & scientifically proven strategies. Get your free eBook now!

Sophie
Feb 261 min read
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